2618-22-6

Hadacidin sodium is a competitive inhibitor of adenylate synthase. Hadacidin sodium binds to the active site of adenylate synthase, competitively inhibiting L-aspartate binding. Hadacidin sodium can be used in drug design, to help develop new inhibitors or activators to regulate adenylate synthase activity, and to play a role in the study of related diseases[1].

[1] Z Hou, et al. IMP alone organizes the active site of adenylosuccinate synthetase from Escherichia coli. Journal of Biological Chemistry 277.8 (2002): 5970-5976. DOI:10.1074/jbc.M109561200