Usage
Coccidiostat (for poultry).
Usage
Lasalocid is a polyether ionophore with potent antibacterial activity. Lasalocid was developed as an animal health product for treatment of coccidia. Lasalocid is able to form neutral complexes with monovalent and divalent cations and transport the ions through apolar phase, including lipid bilayer membranes. Interestingly, lasalocid can also transport larger organic cations, e.g. protonated dopamine.
Usage
Lasalocid sodium is a salt of the polyether ionophore lasalocid, with potent antibacterial activity. Lasalocid was developed as an animal health product for treatment of coccidia. Lasalocid is able to form neutral complexes with monovalent and divalent cations and transport the ions through apolar phase, including lipid bilayer membranes. Interestingly, lasalocid can also transport larger organic cations, e.g. protonated dopamine.
Chemical Properties
White to brown powder with a characteristic odor, melting point 191-192°C (decomposition). Slightly soluble in water, soluble in most organic solvents. Stable, with a shelf life of 6 months at 37°C and 18 months at 25°C. Oral LD50 in mice is 146 mg/kg, and in chickens it is 75-112 mg/kg.
Uses
Coccidiostat (for poultry).
Uses
Lasalocid is a polyether ionophore with potent antibacterial activity. Lasalocid was developed as an animal health product for treatment of coccidia. Lasalocid is able to form neutral complexes with monovalent and divalent cations and transport the ions through apolar phase, including lipid bilayer membranes. Interestingly, lasalocid can also transport larger organic cations, e.g. protonated dopamine.
Uses
Lasalocid sodium is a salt of the polyether ionophore lasalocid, with potent antibacterial activity. Lasalocid was developed as an animal health product for treatment of coccidia. Lasalocid is able to form neutral complexes with monovalent and divalent cations and transport the ions through apolar phase, including lipid bilayer membranes. Interestingly, lasalocid can also transport larger organic cations, e.g. protonated dopamine.
Definition
ChEBI: Lasalocid sodium is the sodium salt of lasalocid. It is a veterinary ionophore antibiotic used for prevention and treatment of coccidiosis in poultry. It has a role as a coccidiostat and an ionophore. It is a member of benzoates and an organic sodium salt. It contains a lasalocid(1-).
