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Pomalidomide-piperazine-propanoic acid is a functionalized Cereblon ligand used for development of pomalidomide-based degrader building blocks. Contains a terminal carboxyl group, allowing rapid conjugation of amine containing linkers. A basic building block for development of a protein degrader library.
Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
Protein Degrader Building Blocks