ChemicalBook CAS DataBase List 2516243-54-0

2516243-54-0

Name	Adintrevimab
CAS	2516243-54-0

Chemical Properties

form	Liquid
color	Colorless to light yellow

ShangHai Biochempartner Co.,Ltd

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Guangzhou Hongyuan Chemical Co.,Ltd

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Wuhan Chemstan Biotechnology Co., Ltd.

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Beijing Jin Ming Biotechnology Co., Ltd.

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Biolab Reagents

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Wuhan Acumen Bio-Technology Co.,ltd

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Wanxin Biotechnology (Jiaxing) Co., LTD

Telephone0573-83568680 18057391398

Website

Atagenix Laboratories

Telephone027-87008169 17762441161

Websitehttps://www.abinscience.com/

Wuhan Maixi Biotechnology Co., Ltd

Telephone18007167883 18007167883

Websitehttps://www.mabnus.cn

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Animal Model:	Syrian golden hamsters (5-6-week-old females; 75-125 g) infected with SARS-CoV-2/WA1/2020^[1].
Dosage:	9.25, 55, 333, or 2,000?μg (average range: 0.1 to 20?mg/kg)
Administration:	Intraperitoneal injection; single dose
Result:	Showed significant reduction in lung viral load and virus-induced lung pathology.

Animal Model:	Rhesus macaques (5.6-8.8?years old; 6 females [4.4-6.3?kg] and 6 males [6.1-8.5?kg]) infected with SARS-CoV-2/WA1/2020^[1].
Dosage:	5?mg/kg, 25?mg/kg
Administration:	Intravenous injection; single dose
Result:	Reduced pulmonary inflammation.