2444815-73-8

Name	BPK-29 hydrochloride
CAS	2444815-73-8
Molecular Formula	C26H33Cl2N3O3
Molecular Weight	506.47
MOL File	2444815-73-8.mol

Synonyms

BPK-29 hcl BPK-29 hydrochloride inhibit,BPK 29,BPK29,BPK-29,Inhibitor,BPK 29 hydrochloride,BPK29 hydrochloride

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Chemical Properties

storage temp.	Store at -20°C
solubility	DMSO: 62.5 mg/mL (123.41 mM)
form	Solid
color	White to off-white

Hazard Information

Description

BPK-29 hydrochloride is a specific ligand that disrupts the atypical orphan nuclear receptor NR0B1-protein (such RBM45 and SNW1) interactions by covalently modifying C274. BPK-29 hydrochloride impairs the anchorage-independent growth of KEAP1-mutant cancer cells[1].

BPK-29 hydrochloride substantially engages NR0B1 with good overall proteomic selectivity in KEAP1-mutant Non-Small Cell Lung Cancers[1].

References

[1]. Bar-Peled L, et al. Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer. Cell. 2017 Oct 19;171(3):696-709.e23.

Spectrum Detail

BPK-29 hydrochloride(2444815-73-8)¹HNMR

Supplier

Shanghai Lollane Biological Technology Co.,Ltd.

Telephone021-52996696，15000506266 15000506266

Websitehttp://www.bioll.com

TargetMol Chemicals Inc.

Telephone 4008200310

Websitehttps://www.targetmol.cn/

Shanghai Yifei Biotechnology Co. , Ltd.

Telephone021-65675885 18964387627

Websitehttp://www.efebio.com

https://hanhongsci.com/

Telephone021-54306202 18917919676

Websitehttps://www.hanhongsci.com/

Telephone

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