2410277-69-7

Name	Cholan-24-oic-23,23-d2 acid, 3-hydroxy-, (3β,5α)-
CAS	2410277-69-7
Molecular Formula	C24H40O3
Molecular Weight	376.58
MOL File	2410277-69-7.mol

Synonyms

5alpha-Cholanic Acid-3beta-ol-23,23-d2 Cholan-24-oic-23,23-d2 acid, 3-hydroxy-, (3β,5α)-

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Chemical Properties

form	Solid
color	White to off-white

Hazard Information

Uses

Isoallolithocholic acid-d2 is the deuterium labeled Isoallolithocholic acid (HY-B0172A). Isoallolithocholic acid is a T cell regulator and enhances regulatory T cells (Tregs) differentiation[1][2].

References

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Hang S, et al. Bile acid metabolites control TH17 and Treg cell differentiation. Nature. 2019 Dec;576(7785):143-148. DOI:10.1038/s41586-019-1785-z

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