TRPA1-IN-1 is a potent, selective, and orally bioavailable TRPA1 small molecule antagonist.
References
[1] Terrett JA, et al. Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron Microscopy. J Med Chem. 2021 Apr 8;64(7):3843-38 DOI:10.1021/acs.jmedchem.0c02023
