2376146-48-2

Azenosertib (80 mg/kg; p.o.; 28 days) inhibits tumor growth in A427 xenograft NOD/SCID mice model^[1].
Azenosertib (10 mg/kg, p.o.) shows plasma exposure C_max of 2.1 μM, a half-time T_1/2 of 2.3 h, an AUC_{0-24 h} of 9.7 μM·h, and an oralbioavailability of F=142% in beagle dog model^[1].