Sodium metabisulfite (96 g, 507 mmol, 2.0 equiv) was added to a solution of 3-bromo-N1-(5-(tert-butyl)-[1,1′-biphenyl]-2-yl)benzene-1,2-diamine (100 g, 253 mmol, 1.0 equiv) and 3,5-di-tert-butyl-2-hydroxybenzaldehyde (83 g, 355 mmol, 1.4 equiv) in N, N-dimethyl formamide (600 mL). After that, the reaction mixture was heated to 110° C. After 16 hours. Water (900 mL) was added to the cooled reaction mixture. The suspension was filtered and the sticky solid was washed with water (100 mL). The solid was triturated with methanol (3×200 mL) to give 2-(4-bromo-1-(5-(tert-butyl)-[1,1'-biphenyl]-2-yl)-1H-benzo[d]imidazol-2-yl)-4,6-di-tert-butylphenol.
![Phenol, 2-[4-bromo-1-[5-(1,1-dimethylethyl)[1,1'-biphenyl]-2-yl]-1H-benzimidazol-2-yl]-4,6-bis(1,1-dimethylethyl)-](/NewsImg/2023-10-07/6383228266431243679450138.jpg "Phenol, 2-[4-bromo-1-[5-(1,1-dimethylethyl)[1,1'-biphenyl]-2-yl]-1H-benzimidazol-2-yl]-4,6-bis(1,1-dimethylethyl)-")
