2361304-26-7

STAT3-IN-3 is a potent and selective inhibitor of signal transducer and activator of transcription 3 (STAT3), with anti-proliferative activity. STAT3-IN-3 induces apoptosis in breast cancer cells. STAT3-IN-3 acts as a promising mitochondria-targeting STAT3 inhibitor for cancer research[1].

STAT3-IN-3 is a potent and selective STAT3 inhibitor with antiproliferative activity. It can induce apoptosis in breast cancer cells. It is a promising mitochondria-targeted STAT3 inhibitor for cancer research.

STAT3

STAT3

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[1] Cai G, et al. Discovery of fluorescent coumarin-benzo[b]thiophene 1, 1-dioxide conjugates as mitochondria-targeting antitumor STAT3 inhibitors. Eur J Med Chem. 2019 Jul 15;174:236-251. DOI:10.1016/j.ejmech.2019.04.024