ChemicalBook CAS DataBase List 2311863-36-0

2311863-36-0

Name	Methanone, [4-(6-amino-3-pyridazinyl)-1-piperidinyl][5-(4-fluorophenoxy)-4-methoxy-2-pyridinyl]-
CAS	2311863-36-0
Molecular Formula	C22H22FN5O3
Molecular Weight	423.44
MOL File	2311863-36-0.mol

Chemical Properties

Boiling point	689.6±55.0 °C(Predicted)
density	1.325±0.06 g/cm3(Predicted)
form	Solid
pka	5.26±0.10(Predicted)
color	White to off-white

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WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.

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TargetMol Chemicals Inc.

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Animal Model:	LPS-induced mice^[1]
Dosage:	1, 3, and 10 mg/kg
Administration:	Oral administration; orally 12 h and 2 h before LPS challenge
Result:	Reduced BALF protein concentration of 56 % at 3 mg/kg and 62 % at 10 mg/kg.

Animal Model:	H1N1-induced mice^[1]
Dosage:	3 mg/kg
Administration:	Oral administration; daily, for 4 days
Result:	Inhibited Evans blue extravasation from the blood to the BALF and reduced BALF Evans blue by 24 % at 3 mg/kg.

2311863-36-0

Chemical Properties

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in vivo

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