Description
A series of 2,5-
dimethoxyphenethylamines, substituted at the four position of the aromatic ring, have psychoactive effects.
1,2 2C-
B (hydrochloride) is a hallucinogenic designer drug that activates the serotonin receptor 5-
HT
2C (pEC
50 = 6.8 for arachidonic acid release) and has emerged as a drug of abuse.
1,2,3 bk-2C-B is a β-ketone analog of 2C-B.
4 This product is intended for forensic and research purposes.
References
1. Bruno, R., Matthews, A.J., Dunn, M., et al. Emerging psychoactive substance use among regular ecstasy users in Australia Drug Alcohol Depend. 124(1-2),19-25(2012).
2. Moya, P.R., Berg, K.A., Gutiérrez-Hernandez, M.A., et al. Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors J. Pharmacol. Exp. Ther. 321(3),1054-1061(2007).
3. Maurer, H.H. Chemistry, pharmacology, and metabolism of emerging drugs of abuse Ther. Drug Monit. 32(5),544-549(2010).
4. Westphal, F., Junge, T., Girreser, U., et al. Structure elucidation of a new designer benzylpiperazine: 4-Bromo-2,5-dimethoxybenzylpiperazine Forensic Sci. Int. 187(1-3),87-96(2009).
