2252375-14-5

Cepadacursen sodium is a liver-targeting antisense oligonucleotide (ASO), inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9) protein synthesis. Cepadacursen sodium can be used for hypercholesterolemia treatment and the prevention of atherosclerotic cardiovascular disease (ASCVD).

[1] Chen W, Wu X, Hu J, et al. The translational potential of miR-26 in atherosclerosis and development of agents for its target genes ACC1/2, COL1A1, CPT1A, FBP1, DGAT2, and SMAD7.?Cardiovasc Diabetol. 2024;23(1):21. Published 2024 Jan 9. doi:10.1186/s12933-024-02119-z DOI:10.1186/s12933-024-02119-z