2243736-37-8

MUN36378 is a FTO inhibitor for treatment of leukemia. This compound was first reported in patent WO 2018157842. This product has no formal name at the moment.

FTO-IN-7 is an inhibitor of FTO. FTO-IN-7 can be used in study Alzheimer's diseases, breast cancers, small-cell lung cancers,a human bone marrow striated muscle cancer, a pancreatic cancer, malignant glioblastoma[1].

[1] Yang, Caiguang, et al.Preparation of 2-substituted-benzene matrix compounds as FTO inhibitors.China,WO2018157843.2018-09-07.
[2] Liu Z, Duan Z, Zhang D, et al. Structure-Activity Relationships and Antileukemia Effects of the Tricyclic Benzoic Acid FTO Inhibitors. J Med Chem. 2022;65(15):10638-10654. DOI:10.1021/acs.jmedchem.2c00848