2241808-52-4

Bersiporocin is a prolyl-tRNA synthetase inhibitor. Bersiporocin has an IC50 of ≤100 nM for phosphoribosylpyrophosphate synthetase (PRS). Bersiporocin can be used for the research of antifibrotic[1][2].

PRS: ≤100 nM (IC₅₀)

[1] Bong-Yong Lee, et al. Heterocyclic compounds, preparation methods, pharmaceutical compositions, and use as pyrolyl-tRNA synthetase inhibitors.WO2018147626 A1
[2] WHO Drug Information, Vol. 35, No. 4, 2021. Geneva: World Health Organization; 2022.