2215027-46-4

DPP-4-IN-1 (compound d1) is a potent DPP-4 (dipeptidyl peptidase 4) inhibitor, with an IC50of 49 nM. DPP-4-IN-1 is a structurally analogs of Alogliptin.html" class="link-product" target="_blank">Alogliptin (HY-A0023A). DPP-4-IN-1 can be used for diabetes research[1].

DPP-4: 49 nM (IC₅₀)

[1] Shen J, et al. Structural optimization of pyrazolo[1,5-a]pyrimidine derivatives as potent and highly selective DPP-4 inhibitors. Eur J Med Chem. 2020 Dec 15;208:112850. DOI:10.1016/j.ejmech.2020.112850