GB1490 is an orally active galectin inhibitor with Kd values of 0.4 μM and 2.7 μM for galectin-1 and galectin-3, respectively[1].
IC 50
Galectin-1: 0.4 μM (Kd); Galectin-3: 2.7 μM (Kd)
References
[1] Fredrik R Zetterberg, et al. Discovery of Selective and Orally Available Galectin-1 Inhibitors. J Med Chem. 2023 Dec 7. DOI:10.1021/acs.jmedchem.3c01787
