Synthesis
Respectively, to take propylene glycol 680mg, sodium hydrogen 2.5g added to 100 ml round bottom flask,THF was added to 10 ml of a solution and stirred for 30 minutes,Then raise the temperature to reflux for 1 hour,And then weigh the bromo-octadecane dispersed in 10 ml of THF by adding a separatory funnel and dropping into the reaction solution,After refluxing the reaction overnight. After completion of the reaction, a saturated sodium chloride solution was added,Dichloromethane extraction three times, combined extract, filter evaporated solvent, crude column chromatography separation,The second band was collected, the resulting product, 550 mg, yield 17.1%.
