ChemicalBook CAS DataBase List 2110426-27-0

2110426-27-0

Name	TRC253
CAS	2110426-27-0
Molecular Formula	C23H21F3N6O2S
MDL Number	MFCD31922706
Molecular Weight	502.51
MOL File	2110426-27-0.mol

Chemical Properties

Boiling point	672.3±65.0 °C(Predicted)
density	1.53±0.1 g/cm3(Predicted)
pka	9.56±0.10(Predicted)

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ChemShuttle, Inc.

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Finetech Industry Limited

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Shanghaizehan biopharma technology co., Ltd.

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Shanghai YuanYe Biotechnology Co., Ltd.

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ShangHai Biochempartner Co.,Ltd

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Shanghai Rechem science Co., Ltd.

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Changzhou Yongfeng Biomedicine Co. Ltd.

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Finetech Industry Limited

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Changzhou Chenhong Biotechnology Co., Ltd.

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Wuxi Donghe Pharmaceutical Technology Co., Ltd.

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Shanghai Luofa Biochemical Technology Co., Ltd.

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Nantong Hi-Future Biotechnology Co., Ltd

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Qi Qi hang Biotechnology Co., Ltd.

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Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.

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Animal Model:	Castrated SHO mice with prostate LNCaP SRα F877L tumor^[1]
Dosage:	30 mg/kg
Administration:	P.o. once daily for 72 days
Result:	Inhibited the tumor growth by 87%.

Animal Model:	CD-1 male mice^[1]
Dosage:	2 mg/kg for i.v.; 10 mg/kg for p.o. (Pharmacokinetic Analysis)
Administration:	Intravenous administration and oral administration
Result:	I.v.: T_1/2=5.99 h; CL=15.0 mL/min/kg; Vdss=6.11 L/kg. P.o.: F=45%; C_max=0.66 μM; AUC_last=4.9 μg?h/mL.

2110426-27-0

Chemical Properties

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in vivo

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