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N-(Biotin)-N-bis(PEG1-alcohol) is a branched PEG linker with biotin and hydroxyl moieties. The branches are all connected to a central nitrogen atom. The biotin group is used for the conjugation of proteins and can also be used for labeling. The alcohol groups can react to further derivatize the compound.

N-(Biotin)-N-bis(PEG1-alcohol) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PEGs

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005