2100306-62-3

N-(Propargyl-PEG2)-N-bis(PEG1-alcohol) is a multi-arm linker that can form triazole linkage with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry.

Propargyl-PEG2-N-bis(PEG2) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG2-N-bis(PEG2) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

PEGs

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005