2098497-25-5

Name	2,2,2-trifluoroacetic acid
CAS	2098497-25-5
Molecular Formula	C36H67ClF3N11O7
Molecular Weight	858.45
MOL File	2098497-25-5.mol

Synonyms

N-[(2S)-1-[[(2S)-1-[[(2S)-6-Amino-1-[[(3S)-1-chloro-6-(diaminomethylideneamino)-2-oxohexan-3-yl]amino]-1-oxohexan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]decanamide

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Chemical Properties

storage temp.	-20°C, away from moisture
form	Solid
color	White to off-white
Water Solubility	Water : 4 mg/mL (4.66 mM; Need ultrasonic)

Hazard Information

Biological Activity

Decanoyl-RVKR-CMK (DecRVKRcmk) TFA inhibits over-expressed gp160 processing and HIV-1 replication[1]. Decanoyl-RVKR-CMK (DecRVKRcmk) TFA inhibits HIV-2ROD replication by blocking envelope glycoprotein precursor processing in the Jurkat lymphocyte cell[1].Decanoyl-RVKR-CMK (DecRVKRcmk) TFA blocks regulated secretion of VGF[2].

References

[1]. B Bahbouhi, et al. Inhibition of HIV-2(ROD) replication in a lymphoblastoid cell line by the alpha1-antitrypsin Portland variant (alpha1-PDX) and the decRVKRcmk peptide: comparison with HIV-1(LAI). Microbes Infect. 2001 Nov;3(13):1073-84. [2]. Angelo L Garcia, et al. A prohormone convertase cleavage site within a predicted alpha-helix mediates sorting of the neuronal and endocrine polypeptide VGF into the regulated secretory pathway. J Biol Chem. 2005 Dec 16;280(50):41595-608.

Supplier

Hangzhou Peptidego Biotech Co.,Ltd.

Telephone0571-87213919

Websitehttp://www.peptidego.com

Nanchang Tianzhen Biotechnology Co., Ltd

Telephone 13173652190

Websitehttp://www.tanzhenbio.com

Hangzhou Sinoda Pharmaceutical Technology Co. LTD

Telephone0571-87213919 17306812703

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList1355681/0.htm

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