2098346-26-8

Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor, is synthesized principally in the stomach.1 It stimulates food intake and transduces signals to hypothalamic regulatory nuclei that control energy homeostasis.2 It is a peptide of 28 amino acids, in which the serine 3 residue is n-octanoylated, which is necessary for biological activity.1,3WARNING This product is not for human or veterinary use.

[1] MASAYASU KOJIMA. Ghrelin is a growth-hormone-releasing acylated peptide from stomach[J]. Nature, 1999, 402 6762: 656-660. DOI: 10.1038/45230
[2] K G MURPHY  S R B. Gut hormones in the control of appetite.[J]. Experimental Physiology, 2004, 89 5: 507-516. DOI: 10.1113/expphysiol.2004.027789
[3] JESUS A GUTIERREZ. Ghrelin octanoylation mediated by an orphan lipid transferase.[J]. Proceedings of the National Academy of Sciences of the United States of America, 2008, 105 17: 6320-6325. DOI: 10.1073/pnas.0800708105