2097826-24-7

Name	Yhhu-3792
CAS	2097826-24-7
Molecular Formula	C24H24N4O2
Molecular Weight	400.47
MOL File	2097826-24-7.mol

Synonyms

Yhhu-3792 2,4-Quinazolinediamine, 5-(3-methoxyphenoxy)-N2-[4-(1-methylethyl)phenyl]-

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Chemical Properties

Boiling point	608.8±65.0 °C(Predicted)
density	1.239±0.06 g/cm3(Predicted)
form	Solid
pka	7.81±0.30(Predicted)
color	Light yellow to yellow

Hazard Information

Uses

Yhhu-3792 enhances the self-renewal capability of neural stem cells (NSCs). Yhhu-3792 activates Notch signaling pathway and promotes the expression of Hes3 and Hes5. Yhhu-3792 expands the NSCs pool and promotes endogenous neurogenesis in the hippocampal dentate gyrus (DG) in mouse. Yhhu-3792 increases the spatial and episodic memory abilities of mice. Yhhu-3792 has the potential for the research of impairment of learning and memory associated DG dysfunction[1].

References

[1] Lu H, et al. A Novel 2-Phenylamino-Quinazoline-Based Compound Expands the Neural Stem Cell Pool and Promotes the Hippocampal Neurogenesis and the Cognitive Ability of Adult Mice. Stem Cells. 2018 Aug;36(8):1273-1285. DOI:10.1002/stem.2843

Supplier

Shanghai Rechem science Co., Ltd.

Telephone021-31433387 15618786686

Websitehttp://cn.rechemscience.com

DC Chemicals

Telephone021-58447131 13564518121

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList927327/0_EN.htm

Suzhou Zhixin Biotechnology Co., Ltd.

Telephone0512-65118909 18100677375

Websitehttp://www.szzxbio.com/

Anqing YanZhi Pharma Discovery Co.,Ltd.

Telephone 18055651951

Website

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

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