2095244-52-1

Name	E3 ligase Ligand-Linker Conjugates 38
CAS	2095244-52-1
Molecular Formula	C46H64N4O12S2
MDL Number	MFCD32197269
Molecular Weight	929.15
MOL File	2095244-52-1.mol

Synonyms

cIAP1 Ligand-Linker Conjugates 12 E3 ligase Ligand-Linker Conjugates 38 Benzenesulfonic acid, 4-methyl-, 2-[2-[2-[2-[3-[[2-[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-[[(1,1-dimethylethoxy)carbonyl]methylamino]-1-oxopropyl]amino]acetyl]-2-pyrrolidinyl]-4-thiazolyl]carbonyl]phenoxy]ethoxy]ethoxy]ethoxy]ethyl ester

show less show more

Chemical Properties

Boiling point	999.9±65.0 °C(Predicted)
density	1.239±0.06 g/cm3(Predicted)
pka	14.02±0.46(Predicted)

Hazard Information

Uses

cIAP1 Ligand-Linker Conjugates 12 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 12 can be used to design SNIPERs[1].

IC 50

cIAP1

References

[1] Ohoka N, et al. In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs). J Biol Chem. 2017 Mar 17;292(11):4556-4570. DOI:10.1074/jbc.M116.768853

Supplier

Jilin Province Woda Biotechnology Co., Ltd.

Telephone 13504435624

Websitehttps://www.wodapro.com

ShenZhen Trendseen Biological Technology Co.,Ltd.

Telephone 13417589054

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList312717/0_EN.htm

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

Henan Mengtai Pharmaceutical Technology Co., Ltd

Telephone17634413542

Websitehttps://www.henanmengtai.com

Adooq Bioscience LLC

Telephone400-025-6535

Websitehttp://www.adooq.cn

Related Products

2095244-42-9 2222354-20-1

1312302-14-9 2357114-75-9

1239943-19-1 2357114-70-4

1351169-40-8 2113688-20-1

1225433-96-4 2241489-43-8

PROMPT×

PROMPT
The What'sApp is temporarily not supported in mainland China

Cancel

Determine

Send Inquriy