20950-52-1

3,7-DMF is an orally active inhibitor of TGF-β1-induced activation of HSCs. 3,7-DMF induces antioxidant genes and quenches ROS away, which can be used to study liver fibrosis[1].

ChEBI: 3,7-dimethoxy-2-phenyl-1-benzopyran-4-one is a member of flavonoids and an ether.

[1] Hyomin Park , et al. Discovery of 3,7-dimethoxyflavone that inhibits liver fibrosis based on dual mechanisms of antioxidant and inhibitor of activated hepatic stellate cell. Free Radic Biol Med.2023, 204. DOI:10.1016/j.freeradbiomed.2023.05.001