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6β-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone . It is formed from eplerenone by the cytochrome P450 (CYP) isoform CYP3A4.

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6-B-HYDROXY EPLERENONE is a metabolite of Eplerenone, which is used alone or in combination with other medications to treat high blood pressure. 6-B-HYDROXY EPLERENONE is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.

A metabolite of Eplerenone, which is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.

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[1] CHYUNG S COOK. Involvement of CYP3A in the metabolism of eplerenone in humans and dogs: differential metabolism by CYP3A4 and CYP3A5.[J]. Drug Metabolism and Disposition, 2002, 30 12: 1344-1351. DOI: 10.1124/dmd.30.12.1344