ChemicalBook CAS DataBase List 207678-81-7

207678-81-7

Name	HS014
CAS	207678-81-7
Molecular Formula	C71H94N20O17S2
MDL Number	MFCD02179654
Molecular Weight	1563.76
MOL File	207678-81-7.mol

Synonyms

HS014 mc4receptor antagonist M.W. 1563.77 C71H94N20O17S2 Melanocortin 4 Receptor antagonist (AC-CYS11,D-2-NAL14,CYS18)-BETA-MSH (11-22) AMIDE Acetyl-(Cys11,D-2-Nal14,Cys18)-b-MSH (11-22) aMide Acetyl-(Cys11,D-2-Nal14,Cys18)-β-MSH (11-22) amide (ACETYL-CYS11-BETA-(2-NAPHTHYL)*-D-ALA14,CYS18)-BET Acetyl-(Cys11,D-2-Nal14,Cys18)-Beta-MSH (11-22) amide Acetyl-(Cys11,D-2-Nal14,Cys18)-β-MSH (11-22) aMide HS014 (Ac-Cys11,D-Ala(2-naphthyl)14,Cys18)-b-MSH (11-22) amide AC-CYS-GLU-HIS-D-2-NAL-ARG-TRP-GLY-CYS-PRO-PRO-LYS-ASP-NH2 AC-CYS-GLU-HIS-D-NAL(2)-ARG-TRP-GLY-CYS-PRO-PRO-LYS-ASP-NH2 (AC-CYS11,D-ALA(2-NAPHTHYL)14,CYS18)-BETA-MSH (11-22) AMIDE MC4 Receptor antagonist, Melanocortin 4 Receptor antagonist Ac-Cys-Glu-His-D-Nal(2)-Arg-Trp-Gly-Cys-Pro-Pro-Lys-Asp-NH2 (Disulfide bridge Cys1-Cys8) [acetyl-cys11, β-(2-naphthyl)-d-ala14, cys18]-β-melanocyte stimulating hormone fragment 11-22 [ACETYL-CYS11, B-(2-NAPHTHYL)-D-ALA14, CYS18]-BETA-MELANOCYTE STIMULATING HORMONE FRAGMENT 11-22 L-α-Asparagine, N-acetyl-L-cysteinyl-L-α-glutamyl-L-histidyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-L-tryptophylglycyl-L-cysteinyl-L-prolyl-L-prolyl-L-lysyl-, cyclic (1→8)-disulfide

Chemical Properties

density	1.57±0.1 g/cm3(Predicted)
storage temp.	−20°C
form	solid
pka	4.07±0.10(Predicted)
Water Solubility	Soluble to 1 mg/ml in water
Sequence	Ac-Cys-Glu-His-{D-2Nal}-Arg-Trp-Gly-Cys-Pro-Pro-Lys-Asp-NH2 (Disulfide bridge:Cys1-Cys8)

Safety Data

Safety Statements	22-24/25 less more
WGK Germany	3

Hazard Information

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in vivo

IC 50

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