ChemicalBook CAS DataBase List 2056-98-6

2056-98-6

Name	2'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE LITHIUM SALT
CAS	2056-98-6
EINECS(EC#)	218-153-9
Molecular Formula	C9H16N3O13P3
MDL Number	MFCD00672272
Molecular Weight	467.16
MOL File	2056-98-6.mol

Synonyms

5'-DCTP DCTP, LI Deoxy-CTP ((2R,3S,5R) Deoxy-5'-CTP DCTP LI-SALT dCTP.Free Acid dCTP - 100mmol solution deoxycytidine-triphosphate 2'-deoxycytidine triphosphate Deoxycytidine 5'-triphosphate -3-hydroxytetrahydrofuran-2-yl) methyl tetrahydrogen triphosphate 2''-DEOXYCYTIDINE 5''-TRIPHOSPHATE (DCTP) 2'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE LITHIUM SALT 2'-DEOXYCYTIDINE-5'-TRIPHOSPHORIC ACID, LITHIUM 2'-Deoxycytidine 5'-(tetrahydrogen triphosphate) Cytidine 5'-(tetrahydrogen triphosphate), 2'-deoxy- 2&#39-DEOXY-CYTIDINE-5&#39-TRIPHOSPHATE LITHIUM SALT 2'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE LITHIUM SALT USP/EP/BP ((2R,3S,5R)-5-(4-AMino-2-oxopyriMidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)Methyl tetrahydrogen triphosphate [[[5-(4-amino-2-oxo-pyrimidin-1-yl)-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphonic acid

Chemical Properties

Boiling point	811.5±75.0 °C(Predicted)
density	2.38±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
form	Stabilized Aqueous Solution
pka	0.80±0.50(Predicted)
color	White to off-white
Water Solubility	Water : ≥ 35 mg/mL (74.92 mM)

Hazard Information

Uses

Isotope labelled 2’-Deoxycytidine 5’-Triphosphate Triethylamine, a labelled metabolite of 2’-Deoxycytidine, a nucleoside triphosphate that is used whenever DNA is synthesized, such as in the polymerase chain reaction.

Definition

ChEBI: DCTP is a 2'-deoxycytidine phosphate having cytosine as the nucleobase. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a 2'-deoxycytidine phosphate and a pyrimidine 2'-deoxyribonucleoside 5'-triphosphate. It is a conjugate acid of a dCTP(3-).

Biological Activity

Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used in DNA synthesis. Deoxycytidine triphosphate can be used in real-time PCR, cDNA synthesis and DNA sequencing research.

in vitro

Assays of thirteen cell lines, derived from mouse lymphomas, myelomas, myeloid tumors, and a mastocytoma, for sensitivity to growth inhibition by 1-β-D-arabinofuranosylcytosine (ara-C) revealed a spectrum between the most and least sensitive which differed 100-fold from each other. An inverse correlation between sensitivity and cellular Deoxycytidine triphosphate (2′-Deoxycytidine-5′-triphosphate, dCTP) content is found, and this suggested that sensitivity of cells might be increased if the dCTP content was lowered during cell exposure to ara-C.
Deoxycytidine triphosphate trisodium salt is a phosphoethanolamine cytidylyltransferase substrate.

target

Human Endogenous Metabolite

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storage

Store at -20°C

Spectrum Detail

Supplier

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