2054345-67-2

azido-tris(ethylenoxy)-L-alanine TFA Salt contains an L-alanine amino acid residue and a terminal azide group. The azide can react with alkynes under copper-catalyzed Click Chemistry reactions.

Azide-PEG3-C1-Ala is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG3-C1-Ala is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

PEGs

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005