202645-74-7

JHW 007 is a dopamine uptake inhibitor and shows high affinity for the dopamine transporter (1,2,3). It also inhibits the effects of cocaine in a dose-dependent manner.

JHW 007 is a dopamine uptake inhibitor; displays high affinity for the dopamine transporter (DAT) (Ki = 25 nM compared to 1330 and 1730 for NET and SERT respectively). Suppresses the effects of cocaine administration in a dose-dependent manner.

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