200432-86-6

UB 165 Fumarate is a novel presynaptic nicotinic acetylcholine receptor (nAChRs) agonist, which shows immediate potency.

Subtype-selective nicotinic agonist. Full agonist at α 3 β 2- and very weak partial agonist at α 4 β 2- containing nAChRs. K i values are 0.27, 20 (IC 50 ), 2790 and 990 nM for α 4 β 2, α 3, α 7 and α 1 β 1 δ ε respectively.

Store at -20°C