199934-16-2

UCL 1684 is a highly potent and selective, nonpeptidic blocker of the Apamin-sensitive Ca2+-activated K+ channel of which inhibition potentially terminates and protects against atrial fibrillation.

Highly potent, non-peptidic blocker of the apamin-sensitive Ca 2+ -activated K + channel (SK Ca ) (IC 50 = 3 nM in rat sympathetic neurons). Blocks hSK1 and rSK2 channels expressed in HEK 293 cells with IC 50 values of 762 and 364 pM respectively.

Desiccate at RT