199522-35-5

Name	NNC 26-9100
CAS	199522-35-5
Molecular Formula	C22H25BrCl2N6S
MDL Number	MFCD09038560
Molecular Weight	556.35
MOL File	199522-35-5.mol

Synonyms

NNC 26-9100 1-[3-[N-(5-Bromopyridin-2-yl)-N-(3,4-dichlorobenzyl)amino]propyl]-3-[3-(1H-imidazol-4-yl)propyl]thiourea Thiourea, N-[3-[(5-bromo-2-pyridinyl)[(3,4-dichlorophenyl)methyl]amino]propyl]-N'-[3-(1H-imidazol-5-yl)propyl]-

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Chemical Properties

storage temp.	Store at +4°C
solubility	Soluble to 50 mM in DMSO and to 50 mM in ethanol
form	Powder

Hazard Information

Uses

NNC 26-9100 is a Somatostatin (SRIF, somatotropin release inhibiting factor) receptor.

Definition

ChEBI: 1-[3-[(5-bromo-2-pyridinyl)-[(3,4-dichlorophenyl)methyl]amino]propyl]-3-[3-(1H-imidazol-5-yl)propyl]thiourea is an aminopyridine.

Biological Activity

Somatostatin sst 4 receptor agonist that displays > 100-fold selectivity over sst 2 receptors (K i values are 6 and 621 nM for sst 4 and sst 2 receptors respectively). Potently inhibits forskolin-induced cAMP accumulation (EC 50 = 26 nM).

storage

Store at -20°C

Supplier

3B Pharmachem (Wuhan) International Co.,Ltd.

Telephone821-50328103-801 18930552037

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList13285/0.htm

TargetMol Chemicals Inc.

Telephone 4008200310

Websitehttps://www.targetmol.cn/

Nantong QuanYi Biotechnology Co., Ltd

Telephone0513-66337626 18051384581

Websitehttps://www.chemhifuture.com/

Wuhan Topule Biopharmaceutical Co., Ltd

Telephone +8618327326525

Websitehttp://topule.com/

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