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CAS DataBase List
1953181-29-7
1953181-29-7
Name
BRD5814
CAS
1953181-29-7
Molecular Formula
C21H23ClF3NO2
Molecular Weight
413.86
MOL File
1953181-29-7.mol
Synonyms
BRD5814
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Chemical Properties
Boiling point
477.8±45.0 °C(Predicted)
density
1.228±0.06 g/cm3(Predicted)
pka
7.56±0.10(Predicted)
Hazard Information
Description
BRD5814 is a highly brain penetrant β-arrestin biased D2R antagonist.
Uses
BRD5814 is a D2R antagonist. BRD5814 can be used in schizophrenia research[1].
IC 50
D
2
Receptor
References
[1] We?wer M, et al. Functionally Biased D2R Antagonists: Targeting the β-Arrestin Pathway to Improve Antipsychotic Treatment. ACS Chem Biol. 2018 Apr 20;13(4):1038-1047. DOI:
10.1021/acschembio.8b00168
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TargetMol Chemicals Inc.
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15002134094
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https://www.targetmol.cn/
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