195209-04-2

ACPT-II is a metabotropic glutamate receptor agonist, which exerts neuroprotective effects against kainate-induced excitotoxicity in primary neuronal cell and the dorsal hippocampus of rats.

Competitive metabotropic receptor antagonist (K b values are 115, 88 and 77 μ M at mGlu 1a , mGlu 2 and mGlu 4a respectively).