19485-63-3

This alkaloid belongs to the isoquinoline group and is one of the cactus bases being found in Lophocereus schottii. It is a colourless oil giving a crystalline picrate and a styphnate with m.p. 191.5-193°C and 171-2°C respectively. The structure has been established as 1:2:3:4-tetrahydro-7-hydroxy-l-isobutyl-6- methoxy-2-methylisoquinoline. It yields a methyl ether, forming a picrate, m.p. 180-2°C and a styphnate, m.p. 210-2°C. The corresponding ethyl ether also gives a picrate and styphnate with m.p. ISO-3°C and 182-3°C respectively.

ChEBI: Lophocerine is a member of isoquinolines.

The Journal of Organic Chemistry, 24, p. 1106, 1959 DOI: 10.1021/jo01090a018

Bobbitt, Chou., J. Org. Chem., 24, 1106 (1959)