Palmitoyl alkyne-coenzyme A (palmitoyl alkyne-CoA) is a thioester of ω-alkynylated palmitic acid and CoA . It has been used as a chemical reporter to label palmitoylated proteins via click chemistry using various probes, including biotin-azide or 3-azido-7-hydroxycoumarin, in vitro and in vivo.1
References
1. Yap, M.C., Kostiuk, M.A., Martin, D.D.O., et al. Rapid and selective detection of fatty acylated proteins using ω-alkynyl-fatty acids and click chemistry J. Lipid Res. 51(6),1566-1580(2010).
