193022-38-7

RS-104966 is a collagenase inhibitor. It acts by inducing the conformational change in the side-chains of the S1 pocket of MMP-1.

RS-104966 is a potent collagenase-1 (MMP-1) inhibitor. RS-104966 induces a conformational change in the side chains of the S10 pocket of MMP-1[1].

collagenases 1

[1] K?llblad P, et al. Efficient conformational sampling of local side-chain flexibility. J Mol Biol. 2003 Mar 7;326(5):1651-65. DOI:10.1016/s0022-2836(03)00083-4