Uses
3-?Bromopropanoyl Isocyanate is a reagent used in the preparation of pharmaceuticals. It is prepared successfully through the rearrangement of N-Bromosuccinimide.
Definition
3-Bromopropionyl Isocyanate is a derivatizing agent for alcohols, phenols, and arylamines; brominating agent potentially present in N-bromosuccinimide brominations; bifunctional cyclization reagent.
Reactivity Profile
3-Bromopropionyl Isocyanate reacts violently with H2O, and with basic and protic solvents.
Precautions
lachrymator; corrosive; use only in a fume hood; wear protective gloves and preferably a NIOSH-approved respirator. All transfers and reactions should be carried out under anhydrous conditions. Store in a cool dry place, taking care to avoid contamination with protic, basic, or organometallic materials, as these may induce polymerization. Toxicity data for isocyanates are available.
