AI-10-104 is an inhibitor for runt-related transcription factor (RUNX), which enhances the cytotoxicity in myeloma cells[1].
References
[1] Zhou N, et al., RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation. Leukemia. 2019 Aug;33(8):2006-2021. DOI:10.1038/s41375-019-0403-2
