1875036-75-1

BI8626 is a specific inhibitor of the ubiquitin ligase HUWE1 with an IC50 of 0.9 μM[1].

BI8626 is a specific antagonist of the ubiquitin ligase HUWE1 with IC50 of 0.9 μM.

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[1] Peter S, et al. Tumor cell-specific inhibition of MYC function using small molecule inhibitors of the HUWE1 ubiquitin ligase.EMBO Mol Med. 2014 Dec;6(12):1525-41. DOI:10.15252/emmm.201403927