1814-64-8

Name	PAPP
CAS	1814-64-8
Molecular Formula	C19H22F3N3
MDL Number	MFCD00055098
Molecular Weight	349.39
MOL File	1814-64-8.mol

Synonyms

163 LY165 LY-165 LY 165 p-Nh2-pe-tfmpp PAPP (LY-165,163) SELECTIVE 5-HT1A SERO 1-(2-(4-Aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine 4-[2-[4-[3-(Trifluoromethyl)phenyl]-1-piperazinyl]ethyl]benzenamine Benzenamine, 4-(2-(4-(3-(trifluoromethyl)phenyl)-1-piperazinyl)ethyl)- PAPP, p-Aminophenethyl-m-trifluoromethylphenyl piperazine, 4-[2-[4-[3-(Trifluoromethyl)phenyl]-1-piperazinyl]ethyl]benzeneamine

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Chemical Properties

Melting point	83-85 °C
Boiling point	464.1±45.0 °C(Predicted)
density	1.218±0.06 g/cm3(Predicted)
solubility	0.1 M HCl: slightly soluble
form	solid
pka	7.85±0.10(Predicted)
color	off-white

Safety Data

WGK Germany

Hazard Information

Uses

LY-165,163 is a selective 5-HT1A and 5-HT1D serotonin receptor antagonist.

Definition

ChEBI:LY-165163 is a N-arylpiperazine that is piperazine susbtituted by 2-(4-aminophenyl)ethyl and 3-(trifluoromethyl)phenyl groups at positions 1 and 4, respectively. It is a selective 5-HT1A serotonin receptor agonist and 5-HT1D serotonin receptor antagonist. It has a role as a geroprotector and a serotonergic agonist. It is a N-arylpiperazine, a N-alkylpiperazine, a member of (trifluoromethyl)benzenes, a substituted aniline and a primary arylamine. It is functionally related to a 1-(3-(trifluoromethyl)phenyl)piperazine.

Biological Activity

Selective 5-HT1A serotonin receptor agonist and 5-HT1D serotonin receptor antagonist.

Supplier

Energy Chemical

Telephone021-58432009 400-005-6266

Websitehttp://www.energy-chemical.com

Jinan Jiuli Biotechnology Co. , Ltd.

Telephone 15865264761

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList89365/0.htm

Beijing Biocreative Technology Co., Ltd.

Telephone 15522676233

Websitehttp://www.bestbaiao.com/

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

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