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LY-165,163 is a selective 5-HT1A and 5-HT1D serotonin receptor antagonist.

ChEBI:LY-165163 is a N-arylpiperazine that is piperazine susbtituted by 2-(4-aminophenyl)ethyl and 3-(trifluoromethyl)phenyl groups at positions 1 and 4, respectively. It is a selective 5-HT1A serotonin receptor agonist and 5-HT1D serotonin receptor antagonist. It has a role as a geroprotector and a serotonergic agonist. It is a N-arylpiperazine, a N-alkylpiperazine, a member of (trifluoromethyl)benzenes, a substituted aniline and a primary arylamine. It is functionally related to a 1-(3-(trifluoromethyl)phenyl)piperazine.

Selective 5-HT1A serotonin receptor agonist and 5-HT1D serotonin receptor antagonist.