SC-55858 is an effective superoxide dismutase simulator. SC-55858 increased heart rate and decreased mean arterial pressure and left ventricular systolic and end-diastolic pressures in conscious dogs[1].
References
[1] Lowe D, et al. Comparison of the cardiovascular effects of two novel superoxide dismutase mimetics, SC-55858 and SC-54417, in conscious dogs. Eur J Pharmacol. 1996 May 23;304(1-3):81-6. DOI:10.1016/0014-2999(96)00120-3
