ATX-002 is an ionizable cationic lipid for RNA drug delivery. The calculated pKa (c-pKa) and measured pKa values for ATX-002 are 8.68 and 6.03, respectively[1].
Biological Activity
ATX-002 is a property-tunable lipid for RNA drug delivery.
References
[1]. Rajappan K, et al. Property-Driven Design and Development of Lipids for Efficient Delivery of siRNA. J Med Chem. 2020 Nov 12;63(21):12992-13012.
