169592-56-7

Name	CASPASE-3
CAS	169592-56-7
MDL Number	MFCD01634593

Synonyms

YAMA CPP32 CPP321 CASP-3 APOPAIN CASPASE-3 YAMA HUMAN CPP32 HUMAN PROCASPASE-3 APOPAIN HUMAN HUMAN CASPASE-3 CASPASE-3, HUMAN Apopain precursor CPP32, ACTIVE FORM CASPASE-3 PRECURSOR PROCASPASE-3 (HUMAN) CASPASE-3, ACTIVE FORM Apopain, CPP32, Yama Cysteine protease CPP32 CASPASE-3 (HUMAN) (REC) PRO-CASPASE-3 (HUMAN) (REC) Human CASP3 Protein, His Tag PROCASPASE-3, HIS TAG(R) HUMAN PROCASPASE-3, HIS TAG(R), MOUSE CASPASE-3 (HUMAN) (RECOMBINANT) CASPASE-3 (HUMAN) (ACTIVE) (REC) PRO-CASPASE-3 (HUMAN) (RECOMBINANT) CASPASE-3, HUMAN, RECOMBINANT, E COLI CASPASE-3 (ACTIVE) (HUMAN) (RECOMBINANT) PROCASPASE-3, HUMAN, RECOMBINANT, E COLI CASPASE-3 (HUMAN) (ACTIVE) (RECOMBINANT) Anti-CSPN3 (Cleaved-Asp175) antibody produced in rabbit ANTI-CLEAVED-CASP3 (ASP175) antibody produced in rabbit Anti-CASP3 (p17, Cleaved-Asp175) antibody produced in rabbit

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Chemical Properties

Melting point	127 °C
storage temp.	−70°C
solubility	PBS: soluble
form	buffered aqueous glycerol solution
biological source	rabbit
Specific Activity	≥1450units/μg protein

Safety Data

WGK Germany

Hazard Information

Uses

Caspase 3 human has been used to digest human r-vimentin. It has also been used in caspase-3 inhibition assay and protease inhibition assay.

General Description

Human recombinant C-terminal histidine tagged caspase 3 is a fully active protein consisting of 17 kDa and 13.5 kDa subunits; the 13.5 kDa subunit contains the histidine tag.

Biochem/physiol Actions

Caspase 3 is a member of the CED-3 subfamily of caspases and is responsible for the cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP), the inhibitor of caspase-activated deoxyribonuclease (ICAD), and gelsolin, a protein involved in apoptosis regulation. Caspase?3 is considered to be an effector caspase, activating pro-caspase?6 and pro-caspase?9 in vitro. Caspase 3 can be activated by caspase 8, caspase 6, and granzyme B.

Supplier

Sigma-Aldrich

Telephone021-61415566 800-8193336

Websitehttps://www.sigmaaldrich.cn

Absin Bioscience Inc.

Telephone021-38015121 15000105423

Websitehttps://www.absin.cn/

Shanghai Universal Biotech Co.,Ltd

Telephone 13774214275

Websitehttps://www.univ-bio.com/

Shanghai Yaji Biological Technology Co., Ltd.

Telephone021-34661275 15301693058

Websitehttp://www.yajimall.com/

CUSABIO

Telephone 027-87196173

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList703656/0.htm

zsbio

Telephone400-810-9781

Websitehttp://www.zsbio.com

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