Description
Thalictrum dasycarpum yields this bisbenzy1isoquino1ine alkaloid which is
obtained as an amorphous powder. It has [α]27D- 70° (c 0.89, MeOH) and gives
an ultraviolet spectrum with absorption maxima at 275 and 282 IT1J1. The
alkaloid yields a crystalline oxalate, m.p. 160-2°C; picrate, m.p. 175-7°C and
the methiodide, m.p. 182-3°C. Five methoxyl groups are present and two
methylimino groups.
Uses
Thalidasine (compound 3) is a bisbenzyltetrahydroisoquinoline alkaloid. Thalidasine is a anticancer agent against human colon adenocarcinoma cells. Thalidasine exhibits antileishmanial activity and can be used for Leishmania infection research research[1].
Definition
ChEBI: Thalidasine is a member of isoquinolines and a bisbenzylisoquinoline alkaloid.
References
Kupchan et al., 1. Amer. Chem. Soc., 89,3075 (1967)
