ChemicalBook CAS DataBase List 166095-21-2

166095-21-2

Name	BMS 191095
CAS	166095-21-2
Molecular Formula	C22H21ClN4O2
Molecular Weight	408.88
MOL File	166095-21-2.mol

Chemical Properties

Boiling point	649.4±55.0 °C(Predicted)
density	1.39±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : ≥ 50 mg/mL (122.29 mM)
form	Solid
pka	13.19±0.60(Predicted)
color	White to off-white

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Animal Model:	Male Wistar rats with the induction of ischemia induced by middle cerebral artery occlusion (MCAO)^[3]
Dosage:	2.5 or 25 μg
Administration:	Intraventricular infusion; 30 min/60 min/24 hours before the induction of ischemia, once
Result:	Reduced total infarct volume in rats with of pretreat dose of 25 mg and 24 h before MCA. Induced a rapid mitochondrial depolarization.

166095-21-2

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