1623432-51-8

Name	QGOICCMBEDDFCI-NXQGQTBASA-N
CAS	1623432-51-8
Molecular Formula	C37H41Cl2FN2O7S
MDL Number	MFCD28902225
Molecular Weight	747.7
MOL File	1623432-51-8.mol

Synonyms

AM-7209 AMG7209 AMG-7209 AMG 7209 QGOICCMBEDDFCI-NXQGQTBASA-N Benzoic acid, 4-[[2-[(3R,5R,6S)-6-(4-chloro-3-fluorophenyl)-5-(3-chlorophenyl)-1-[(1S)-1-cyclopropyl-2-[(1,1-dimethylethyl)sulfonyl]ethyl]-3-methyl-2-oxo-3-piperidinyl]acetyl]amino]-2-methoxy-

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Hazard Information

Description

AMG-7209 is a potent and selective inhibitor of the MDM2-p53 interaction.

Uses

AM-7209 is a potent and selective MDM2-p53 interaction inhibitor with a Kd of 38 pM. AM-7209 inhibits the MDM2 amplified SJSA-1 osteosarcoma cell line with an IC50 of 1.6 nM. AM-7209 shows antitumor activities[1].

References

[1] Yosup Rew, et al. Discovery of AM-7209, a potent and selective 4-amidobenzoic acid inhibitor of the MDM2-p53 interaction. J Med Chem. 2014 Dec 26;57(24):10499-511. DOI:10.1021/jm501550p

Supplier

HANGZHOU CLAP TECHNOLOGY CO.,LTD

Telephone86-571-88216897,88216896 13588875226

Websitehttp://www.hzclap.com/en/

Nanjing Shizhou Biology Technology Co.,Ltd

Telephone025-85560043 15850508050

Websitehttp://www.synzest.com

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

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