CAY10701 is a 7-deazahypoxanthine analog that prevents microtubule formation, blocking the proliferation of HeLa and MCF-7 cells (GI50s = 22 and 38 nM, respectively).
Uses
CAY10701 (Compound 20) is a 7-deazahypoxanthine analogue with anticancer activity[1].
References
[1] van der Westhuyzen, et al. "Improved Rigidin-Inspired Antiproliferative Agents with Modifications on the 7-Deazahypoxanthine C7/C8 Ring Systems." Journal of Medicinal Chemistry (2024). DOI:10.1021/acs.jmedchem.5b01426
